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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GREB1L All Species: 9.09
Human Site: S1255 Identified Species: 25
UniProt: Q9C091 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C091 NP_001136438.1 1923 214354 S1255 G K L P S S S S L L P H A D V
Chimpanzee Pan troglodytes XP_512053 1035 116300 F422 P A S G T R N F H P R R L L L
Rhesus Macaque Macaca mulatta XP_001088999 1036 116613 H423 A S G T R N F H P R R L L L T
Dog Lupus familis XP_852477 1949 216541 S1282 S G L P K A A S L L P S H S V
Cat Felis silvestris
Mouse Mus musculus Q3UHK3 1954 216936 S1287 S G L P K S A S L L P S P S V
Rat Rattus norvegicus XP_001071780 1912 213556 L1244 S K L P S S S L L P H A D V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507474 1058 120283 H445 G T S G G G L H P R R L L L T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001344452 1947 215402 S1282 L G H P S S A S L L P H A D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785617 1405 153362 I791 V V R T Y L L I R Q Y S A A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.5 52.6 52.3 N.A. 51.8 90.9 N.A. 48.4 N.A. N.A. 62.8 N.A. N.A. N.A. N.A. 24.6
Protein Similarity: 100 53.6 52.8 67.9 N.A. 67.3 94.6 N.A. 51.6 N.A. N.A. 76.4 N.A. N.A. N.A. N.A. 39
P-Site Identity: 100 0 0 46.6 N.A. 53.3 46.6 N.A. 6.6 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 6.6 60 N.A. 60 46.6 N.A. 6.6 N.A. N.A. 80 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 0 0 12 34 0 0 0 0 12 34 12 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 12 23 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 12 12 0 0 0 0 0 0 0 % F
% Gly: 23 34 12 23 12 12 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 12 0 0 0 0 23 12 0 12 23 12 0 0 % H
% Ile: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 23 0 0 23 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 45 0 0 12 23 12 56 45 0 23 34 34 23 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % N
% Pro: 12 0 0 56 0 0 0 0 23 23 45 0 12 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % Q
% Arg: 0 0 12 0 12 12 0 0 12 23 34 12 0 0 0 % R
% Ser: 34 12 23 0 34 45 23 45 0 0 0 34 0 23 0 % S
% Thr: 0 12 0 23 12 0 0 0 0 0 0 0 0 0 23 % T
% Val: 12 12 0 0 0 0 0 0 0 0 0 0 0 12 45 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 0 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _